Introduction

Hi, I'm Ryan, a doctor and neuroscientist based in London.

I graduated in 2022 from the UCL MB PhD programme, and I am currently completing clinical foundation training in North London. I am an incoming Internal Medicine and Neurology resident in the Academic Clinical Fellowship programme at King's College London.

I love caring for patients, and I love studying the brain. My research focus encompasses these two passions: I use basic experimental methods and clinical data to understand the basis of maladaptive behaviours and cognitive deficits in brain disorders such as Alzheimer's disease.

Work

Relevant publications

1. Wee RWS, Mishchanchuk K, AlSubaie R, Church TW, Gold MG, MacAskill AF. Internal-state-dependent control of feeding behavior via hippocampal ghrelin signaling. Neuron. 2023 Nov 10:S0896-6273(23)00797-3. doi: 10.1016/j.neuron.2023.10.016. Epub ahead of print. PMID: 37977151.


2. Wee RWS, Nash A, Angus-Leppan H. Deep phenotyping of frontal lobe epilepsy compared to other epilepsy syndromes. J Neurol. 2023 Jun;270(6):3072-3081. doi: 10.1007/s00415-023-11639-9. Epub 2023 Feb 27. PMID: 36847847.


3. Sánchez-Bellot C, AlSubaie R, Mishchanchuk K, Wee RWS, MacAskill AF. Two opposing hippocampus to prefrontal cortex pathways for the control of approach and avoidance behaviour. Nat Commun. 2022 Jan 17;13(1):339. doi: 10.1038/s41467-022-27977-7. PMID: 35039510.


4. Al-Subaie R, Wee RWS, Ritoux R, Mishchanchuk M, Regester D, MacAskill AF. 2021. Control of parallel hippocampal output pathways by amygdalar long-range inhibitory projections. Elife. 10:e74758. doi: 10.7554/eLife.74758. PMID: 34845987.


5. Wee RWS, MacAskill AF. 2020. Biased Connectivity of Brain-wide Inputs to Ventral Subiculum Output Neurons. Cell Rep 30:3644–3654.e6. doi:10.1016/j.celrep.2020.02.093. PMID: 32187537

Media coverage

• Hunger hormones impact decision-making part of the brain, study shows. (Nov 2023) The Independent
• Neuroscientists May Have Discovered Where in the Brain We Get Hangry (Nov 2023) Newsweek
• Investigadores descubren la parte del cerebro que está implicada en la regulación del apetito (Nov 2023) ABC (Spain)
• Scientists uncover proof that hunger impacts our decision making (Nov 2023) Evening Standard

CV

Contact

Please do get in touch if you're in the fields of medicine, neuroscience, or related fields.

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Elements

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